Projects

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PANSIMS

Analysis of neuromelanins and metals involved in neurodegeneration of Parkinson’s disease using novel high resolution SIMS methods

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MJFF 12751.02

Parkin Protects Against Dopamine-Induced Neurotoxicity

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FindingMS

An integrated approach to predict disease activity in the early phases of Multiple Sclerosis

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GR4MS

Integration of clinical and multi-omics multiple sclerosis data into a predictive algorithm of disease activity to accelerate personalized medicine

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CONNECTION

Chondroitin sulfate proteoglycan‐4, secreted by a binding imbalance between SP1 and NF‐kB on CHST11 gene, triggers sympathetic cardiac denervation in Duchenne Muscular Dystrophy

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Dissecting the role of heterochromatic conformation in age-related sarcopenia and frailty

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SATISFY

Generation of patient-specific human tissues for testing the efficacy of new drugs

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NUTRAGE - ITB Segrate

NUTRAGE - Ruolo delle proteine TMEM nel NOTCH signaling

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CN3-PNRR

Sviluppo di una innovativa piattaforma di screening per il design di CRISPR ad elevate efficacia e specificità

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Integrated PET/MRI and germline variants to differentiate brain tumor recurrence from iatrogenic changes in children

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Pilot pharmacogenomic study of the smoking cessation therapies

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genomics and transcriptomics of lung adenocarcinoma survival

Complex interactions between genetic variants and lung tissue transcription in the outcome of lung adenocarcinoma

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PAT-COVID

Host genetics and pathogenetic mechanisms of COVID-19

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NUTBRAIN

A `System Epidemiology' Approach to Explore the Complex Relationship between Nutrition and Brain Aging

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Beyond cohesion

Non-canonical roles of cohesin and Separase, beyond that of cohesion

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PROMED-COG

Protein enriched Mediterranean diet and exercise to prevent undernutrition and promote healthy cognitive ageing

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Genome, Environment, Microbiome & Metabolome in Autism: an integrated multi-omic systems biology approach to identify biomarkers for personalized treatment and primary prevention of Autism Spectrum Disorder

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Endothelial Dysfunction in COVID

SARS-CoV-2-induced endothelial cell dysfunction: mechanisms and therapeutic approaches

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P2022NE7JH

Role of Ribosomal protein L8 gene amplification in ovarian cancer

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2020YXFSW5

Structural and functional characterization of the essential transcriptional regulator HP1043 of Helicobacter pylori as target for new antibacterial drugs