Intranet
Staff

Federica Chiappori

Primo Ricercatore
Application Areas
Research Areas
Research Lines
Projects
E-Mail

federica.chiappori@cnr.it

PHONE

+390226422604

LOCATION

Segrate

ROOM (floor/number)

6/05

I am a researcher in bioinformatics at ITB-CNR since 2006, staff researcher since 2020, and senior researcher since 2023. After graduating in Bioinformatics in 2005 and achieving a PhD in Sciences for Environmental and Public Health in 2010, my research focuses on molecular modeling of protein and non-protein structures. I have experience in structure-to-function correlation studies, post-translational (-transcriptional) modifications, interaction analysis, and the design of compounds with potential pharmacological activity, like small molecules and therapeutic RNAs. Principally, applied methods are molecular dynamics and docking for the study of protein-ligand, protein-protein, and protein-RNA complexes, using HPC. More recently, I have expanded my research interests to include metagenomic, transcriptomic, and employed deep learning methods besides to traditional ones. I am an ordinary member of the BITS scientific society.

The use of molecular modeling for detailed studies of the recognition and binding processes of macromolecules of biological and pharmacological interest.

Investigation, High Throughput Virtual Screening (HTVS), rational and de novo design, drug repurposing, and iterative optimization of pharmacologically active molecules and other therapeutic entities (like small molecules and RNAs) aimed at treating or preventing pathological conditions in living organisms.

The study of protein variants, mutations, and post-translational modifications using molecular modelling methods.

Employment of deep learning methods for protein design and engineering

Deployment and application of automated analysis pipelines for the analysis of bulk, single-cell and spatial transcriptomics data.