Staff

Antonella De Palma

Ricercatore
E-Mail

antonella.depalma@cnr.it

PHONE

+390226422732/720

LOCATION

Segrate

ROOM (floor/number)

7/17

I am Antonella De Palma, a researcher at the Proteomics Unit of ITB since 2005. My work focuses on developing and optimizing proteomics protocols using innovative analytical platforms that integrate nano/micro liquid chromatography systems with high-resolution, high-speed mass spectrometers. In recent years, I have specialized in clinical proteomics, applying high-throughput approaches and end-to-end pipelines, from experimental design to data interpretation using dedicated computational tools. My goal is to characterize the proteome in complex biological matrices, investigate molecular mechanisms underlying diseases and drug response, identify diagnostic, prognostic, and predictive biomarkers, and enable patient stratification based on proteomic profiles. Additionally, our unit serves as the national reference for ELIXIR-EU, which has allowed me to contribute at various levels of responsibility to biomedical studies with significant social impact, often in emerging research areas, collaborating with hospitals, research institutions, and industrial partners for technology transfer.

Sample preparation (cell lines, tissues, organs, biofluids, extracellular vesicles).

Proteomic analysis integrating high-resolution and high-speed mass spectrometers with micro- and/or nano-fluidic chromatography systems

Computational analysis and pipeline development for qualitative and quantitative proteome characterization, including network analysis within a systems biology approach.

Development and Optimization of High-Throughput LC‑MS Pipelines for Proteomics Research

Biomarker discovery and validation through LC‑MS–based proteomics for early diagnosis, prognosis, therapy monitoring and patient stratification in precision medicine.

Research services with advanced proteomics technologies for academia and industry, fostering technology transfer, training and open access practices