Francesca A. Cupaioli

I’m a researcher at the Institute for Biomedical Technologies (ITB) of the National Research Council (CNR), where I use next-generation omics technologies by integrating both experimental and computational expertise. I combine molecular biology and advanced computational analysis, with a particular focus on the functional interpretation of multi-omics datasets applied to the study of neurological diseases and cancer immunology. My research activity covers the entire workflow for the generation and analysis of omics data, ranging from the preparation of samples for single-cell transcriptomic profiling and the management of experimental procedures, to the computational analysis and interpretation of single-cell, bulk RNA-seq, and spatial transcriptomics data, as well as the integration of multiple omics layers. My main scientific interests include neurodegeneration, neuroinflammation, and the dynamics of the tumor microenvironment, with the goal of identifying pathogenic and drug-resistance mechanisms and contributing to the development of innovative therapeutic strategies. I collaborate at both national and international levels, primarily with the University of Milan, the University of Pavia, the National Institute of Molecular Genetics, and Vita-Salute San Raffaele University.