Cellular and Tissue Biomedicine

This is a dynamic research area dedicated to investigating the molecular and cellular mechanisms that govern cell and tissue functions across a range of diseases and biological systems. This area encompasses the study of stem cells, exploring their potential to develop into specialized cell types and their role in tissue regeneration and repair. Scientists in this area are at the forefront of developing organoids, three-dimensional, lab-grown miniature organs, which provide advanced models for studying human development, disease progression, and drug responses in a more physiologically relevant context. Researchers additionally utilize cellular reprogramming approaches to induce the conversion of differentiated cells into a pluripotent state (human induced Pluripotent Stem Cells, iPSCs), thereby enabling the generation of patient-specific cells for personalized therapies and disease modelling. Within this framework, research activities focus on the development of advanced patient-specific 3D tissue models and bioengineered constructs for cardiovascular, skeletal muscle, oncological, and neurological applications. These approaches integrate stem cells, extracellular vesicles, biomaterials, and 3D modelling technologies to recapitulate complex tissue microenvironments and support translational and regenerative strategies.