Epigenomics

ITB researchers involved in epigenomics focus on uncovering the molecular mechanisms that link genome regulation to phenotypic diversity and cellular states. The team investigates the genetic and epigenetic determinants underlying phenotypic variability, integrating cutting-edge experimental and computational approaches. Advanced methodologies such as 4f-SAMMY-seq (DNA-seq) are employed to probe genome-wide DNA features, while dedicated studies address the organization and accessibility of bacterial chromosomes, providing insights into prokaryotic genome regulation. In parallel, the group analyzes chromatin remodeling processes and epigenetic alterations across different biological conditions, contributing to a deeper understanding of how epigenetic dynamics influence development, adaptation, and disease.