I am a researcher with over ten years of experience in the field of molecular oncology, with a primary focus on non small cell lung cancer (NSCLC). My scientific career has developed through international research environments, allowing me to build a solid and multidisciplinary background in cancer biology. I began my postdoctoral training at Harvard Medical School in Boston and at the Cancer Science Institute of Singapore, where I strengthened my expertise in cellular and molecular biology applied to cancer research within a highly international and collaborative context. I currently hold a researcher position at the Institute of Biomedical Technologies (ITB) in Pisa. In this role, I actively collaborate with researchers with complementary expertise, including bioinformatics (ITB), biochemistry (ICCOM), medical physics (IFC), and advanced microscopy (FPS). This network of collaborations enables a truly multidisciplinary approach to cancer research, that aims to investigate tumor biology, identify novel molecular targets to inhibit cancer growth, and develop strategies to overcome resistance to existing therapies. My long-term goal is to contribute to the development of more effective and personalized therapeutic approaches for lung cancer patients.
Research Activities
Genome-wide association studies (GWAS) for the identification of germline variants associated with diseases, other binary phenotypes and quantitative traits.
Genome assembly of high resolution, haplotype resolved genomes and polymorphism characterization
Exploring the genetic and epigenetic background underlying phenotype’s variability
Analysis of chromatin remodeling and epigenetic changes in different biological states
Transcriptomic analysis of cancer cells, stem cells, organoids, human and murine tissues in disease models
Transcriptomic profiling for coding and non-coding RNAs biomarker discovery and regulatory pathway analysis
