Research Activities
Study of molecular and cellular mechanisms in tumorigenesis with a focus on dissecting cellular heterogeneity and interactions within the tumor microenvironment
Development of 3D patient-derived organoids recapitulating in vitro disease models to study the interactions between host and components of surrounding microenvironment
Study of neurodevelopmental disorders physiopathology through the generation of patients iPSCs-derived brain organoids as model systems
Investigating the roles of genes involved in age-related diseases to elucidate their molecular mechanisms underlying cellular senescence and tissue damage
Regulation of gene expression by transient or constitutive modulation of genes to provide insights into gene function and therapeutic potential in disease models
Development of high-throughput CRISPR screening platforms, integrating machine learning-guided library design with large-scale genetic perturbation experiments in different biological contexts
